Nearly two decades after the introduction of combined radiation therapy and temozolomide, the Stupp protocol remains the foundation of glioblastoma treatment. In this episode, Roger Stupp, MD, and Rimas Lukas, MD, take a look at how this regimen emerged as a durable standard of care and how clinical insights since then have refined its use. Dr. Stupp and Dr. Lukas walk through the modern care pathway for newly diagnosed glioblastoma and the clinical trial landscape. They dive into why survival gains remain limited and what may finally move the field forward.
