In this episode of Better Edge, Shan H. Siddiqi, MD, discusses how connectivity-based, image-guided neuro-navigation is refining transcranial magnetic stimulation (TMS) protocols for treatment-resistant depression, anxiety and other psychiatric disorders. He details findings from a recent JAMA Psychiatry trial that found that this approach raised response rates from 60% to 80%, with lesion-network mapping potentially expanding TMS use to bipolar disorder, PTSD, OCD and Parkinson's disease. Dr. Siddiqi also highlights Northwestern Medicine's emerging interventional psychiatry program, which integrates TMS, ketamine and ECT services with a broad portfolio of neuromodulation clinical trials and a newly accredited brain stimulation fellowship.