Dr. Kendall Williams: Welcome everyone to the Penn
Primary Care podcast. I'm your host, Dr. Kendall Williams. If you were watching
Monday Night Football a few days ago or a week ago you saw a scene that was
very uncomfortable to watch, early in the game a player for the Buffalo Bills
of DeMar Hamlin suffered a cardiac arrest on the field, probably as a result
of, what otherwise looked like a relatively benign chest blow.

He was down for seven to 10 minutes. The teams gathered around
him, getting chest compressions, and then he was put in an ambulance and taken
to a local Cincinnati hospital. And the entire nation, if you were on Twitter,
was asking questions about what is happening to him and, what's his prognosis
in particular. So, it brought up a lot of very good questions about cardiac
arrest, how to manage cardiac arrest an d what we as physicians can do to promote
cardiac arrest knowledge within the community.

So in order to explore those issues, I brought on an expert in
cardiac arrest at Penn. Dr. Ben Abella is the director for Center for
Resuscitation Science at Penn. He is a Professor of emergency medicine and
critical care as well. his areas of research are in cardiac arrest and all of
the issues that were discussed tonight. Thanks, Ben.

Dr. Ben Abella: It's my pleasure to be with you tonight.

Dr. Kendall Williams: So, Ben, let's just start it. And
this is just gonna be a conversation between you and I and probably a
relatively short one, but let's just start with the situation that happened
when DeMar Hamlin went down. Reports are, that he, Was watched closely by
trainers. They watched the event occur. The trainers reported very early among
themselves or on walkie-talkies and other devices that they were very worried
about a situation and they got out there quickly. And when you first encounter
a patient that goes down in an awkward way and you're worried about cardiac
arrest, what do you do?

Dr. Ben Abella: Yeah, it's a remarkable story and it
certainly has captivated the attention of many. So when someone collapses like
that, there's always a concern that cardiac arrest could be the issue at hand.
And, you it has been known for quite some time that many arrest events, when
people collapse, suddenly they're missed. That is to say people don't recognize
cardiac risk for a period of time. A few basic facts about cardiac arrest, I
think for context. So cardiac arrest strikes around 400,000 people each year in
the United States. So it's certainly common, you know, over a thousand people a
day in the US suffer cardiac arrest.

What's remarkable about the disease is that it is the most time
sensitive disease know of medicine. So what I mean is a hundred percent fatal
unless CPR and or the use of an AED automated external defibrillator, or both
are done within minutes. Every minute spent in cardiac arrest without the
initiation of CPR survival drops by 10%. Now it's not exactly linear, so it's
not that at 10 minutes. There's no hope, but it's asymptotic. So survival if
CPR started 10 minutes later is single percentage points. Survival if CPR
started within the first two minutes can be as high as 50 or 60%. So it really,
really matters to get CPR started right away.

Dr. Kendall Williams: So I didn't mention this up front
and probably should have that DeMar Hamlin is doing fine and he is one of the
success stories. Has been discharged from the hospital, and I assume that's
mostly because he was almost in the ideal place to have this event because he
had professional trainers there who were on the scene immediately and a minute
I think he was getting CPR.

Dr. Ben Abella: That's exactly right. So he had very
prompt recognition and of his arrest event, and then prompt CPR delivery. And
those are the first two links in the so-called Chain of Survival, a Paradigm
for thinking about cardiac arrest that involves five links. First, the prompt
recognition follow. early aggressive CPR followed by the use of a
defibrillator, followed by advanced care, usually by ems, emergency medical
services, if it's an out of hospital arrest. Then finally followed by
post-arrest care, andthat's a whole topic unto itself that we can touch on
later.

But yes, those first two links in the chain of survival are so
important to prompt recognition that someone's in trouble and someone's having
cardiac arrest, and then the initiation of cpr. And by all accounts, he got CPR
started aggressively within a minute or two of his collapse. I don't know if
we'll ever know exactly but it was that quick. And one of the things that was
so remarkable about this, is that in many cases people are slow to recognize it
because people may have signs of movement or quote unquote life that will be
confusing. What do I mean by this?

Well, some young healthy victims in the first few minutes of
cardiac arrest will have agonal breaths or gasping breaths, so that might
confuse a bystander to think they're very much alive and just having a
breathing problem. And some people have seizures full on seizures, as many as
10 to 20% of. Young people with cardiac arrest will have seizures in the first
few minutes of their arrest event. And this is not just from brain ischemia,
but it also is confusing because people might think, oh, they must have a
seizure disorder or not. But for whatever reason, they're being a seizure. In
fact, those things can be immediate signs of cardiac arrest, especially in
young healthy victims.

Dr. Kendall Williams: So the first thing is to check a
pulse.

Dr. Ben Abella: Well, it's interesting, yes and no. so
the old teaching was, yes, the first thing would be to check a pulse and
certainly for trained providers, that is reasonable. The current American Heart
Association guidelines actually for the lay public anyway, and, I guess we're
speaking to sort of a, both a professional audience and a public audience. In
the late public, it's recommended not to check a pulse. And the reason why is
checking a pulse is actually harder than it sounds, especially in one of these
crisis situations where someone might just be feeling their own heartbeat and
not feeling a pulse and confused and thinking there's a pulse.

And so for the lay public, it's felt that the key algorithm is
to see if you can shake the patient a little bit, get their, wake them up. Hey,
hey, are you there? Are you there? And if they don't respond to, then look for
breath. Chest rise, air nostril, flaring or movement of air, which is also not
necessarily the easiest thing, but if someone does not seem to be arousable and
they do not seem to be breathing, to start CPR and assume it's cardiac arrest,

Dr. Kendall Williams: So, my experience checking a pulse
as a medical student was I knew how to do it when a fully patient was fully
alive and having a pulse, but it was a little bit different situation to say
that the patient has no pulse. Because You're always asking yourself, am I
checking in the right spot? And I had at least had some training at that point
of where the pulses should be. But the, as you said, the average lay public. So
that sounds very reasonable. So if a patient doesn't look like they're
breathing and is not responding to you appropriately, just go right to CPR.

Dr. Ben Abella: Yeah. that's right. And in fact, Someone
listening might say, well, what if you're wrong? What if you're doing CPR and
someone who's not in cardiac arrest? Well, that's been studied actually. There
are several case series published of people who got CPR for syncope or drug intoxication,
a non-cardiac arrest reasons were just a well-meaning person just was wrong.
And it turns out they did fine. The incidents of injury is small, the most
commonly reported side effect if you is chest soreness, which certainly makes
sense, but it is pretty hard to cause substantial damage to someone with CPR.

So the teaching is better to be wrong and gives CPR to someone
who doesn't need it, rather than the opposite. And in fact, most people who are
not in cardiac arrest, will find CPR so noxious that they will move or swat at
your hands even if they're intoxicated or, hypotensive or some other condition.
It's pretty rare for someone not in cardiac arrest to have no reaction from
someone pounding on their chest. So the general teaching after much deliberation
at American Heart Association meetings to go through all these data was pretty
clear. Best to start CPR because the bigger problem is people not getting CPR
promptly late recognition of cardiac arrest, which generally leads to poor
outcomes.

Dr. Kendall Williams: So that leads to the next
question, and even for us as doctors who have taken BLS, and I've taken ACLS
several times, I've taken ATLS, I'm not sure in a critical moment where it
happens right in front of you, and you're not thinking about it at all, that, I
would remember exactly how many compressions I'm supposed to give, how often
I'm supposed to give breaths and so forth. I know those numbers because I
looked them up, but in the it sounds like you are saying that the most
important thing is just get there. Start CPR and then work it out from there.
Right?

Dr. Ben Abella: That's right. And most importantly, to
deliver chest compressions. There's very good published data from a number of
studies now showing that the breathing part is less important. Now, the
traditional teaching, of course, is repeated cycles of compressions, breaths.
The current iteration of that is 30 compressions, two breaths, 30 compressions,
two breaths. That said, the evidence is pretty clear that if you only deliver chest
compressions with no breaths, survival is statistically the same. If there's
professional response within five to seven minutes.

What does all that mean? That means that most people who have
cardiac rest do not have a lung problem and they do not have an oxygenation
problem. And it turns out that your blood oxygenation can persist fairly well
for minutes. And so the biggest lesion in cardiac rest is the lack of blood
flow. And so that's what you need to restore. You need to restore the blood
flow. And it is chest compression only that can do that for the victim and so
there has been this large movement, especially for the lay public, to teach
what's called compression only CPR or hands only cpr, where you just deliver
compressions.

And you can imagine this is a very attractive option. It's
easier to teach, it's simpler, you get away from the icky factor of putting
your mouth to some stranger's mouth. And so we actually, from a public health
perspective, may save many more. If we just teach Hands Only CPR, and that's
what is being done in many places. For example, in many high schools they have
CPR as a requirement for graduation and they teach Hands Only CPR.

Dr. Kendall Williams: And let's go into CPR chest
compressions and how to do them well, because the quality of it really matters.
What is the teaching here?

Dr. Ben Abella: Yeah, so it, it's true and there's very
good evidence that the quality of CPR matters quite a lot. And we've done some
of that research at our team at Penn and what we know is that you want to do
compressions at about a hundred to 120 beats per minute. Too fast as bad, and
too slow is bad. And we see in actual practice a wide range of chest
compression rates because people don't have a deeply inherent metronome in
their heads. And so, if you had a metronome, you would set it to a hundred or
110 and do that. Now some defibrillators actually do have metronomes baked in.

So you can hear a sort of a prompt or a clicking noise to
synchronize your compression. Some do not. those who are of a certain age on
this, listening in will know that the metronomic beat of Staying Alive as
recorded by the Bee Gees is about a hundred per minute. There are newer songs
with the same Metron geek for those who are younger. But suffice it to say a
hundred to compressions per minute is what you want. The hands have to be right
over the sternums, over the center of the chest, and you want to push hard.
what do I mean by hard? Well, officially the recommendation is two to 2.4
inches of chest deflection.

Now, the problem, of course, there is no one has a ruler. No
one gets outta ruler what is two inches? So the AHA says push hard, because in
truth it's pretty hard to push more than two inches. Especially more than 2.4
inches. Chest wall compliance is such that the harder you push, the harder it
is to keep going. And so the vast majority of recorded compressions in public
CPR are too shallow. So you really wanna push hard and survival actually
correlates very strongly with depth. So depth really matters.

Dr. Kendall Williams: Because you're trying to, compress
the heart which is obviously, several centimeters below the surface of the
skin, and you're trying to use the chest to push that and get some blood out of
that. Using it as a purely mechanical pump, right?

Dr. Ben Abella: Yeah or said another way. Chest
compressions are just not the way we were designed to move blood throughout our
body. We have an internal pump that's the more efficient way. So these external
compressions are, The best way to do it. And so you just have to push really
hard to have it work because already it's, at its most effective with excellent
depth and rate. CPR can generate blood pressures that perfuse the brain, but no
one is norm intensive. They've actually looked at this and you can generate
with excellent CPR pressures of, you know, 60 over 40 or 70, over 30.

So hypotension that might be very well viable. And in fact,
there are cases, amazingly of people who regain consciousness during CPR,
flutter their eyes and look around with terror in their eyes, wondering what's
going on. Now it's not very common, but it has been reported. So, it's not
enough to keep you going forever. So CPR is really thought of as a bridge. It's
a bridge to definitive care and that definitive care might be defibrillation if
someone's in a shockable rhythm, it might be other interventions. But CPR when
delivered well can be very effective to profuse organs and keep that person
alive until the definitive therapies are.

Dr. Kendall Williams: So I wanna highlight a couple
things just on CPR before we move on, and that is just to highlight what you
said about using the beat to the BeeGees song, Staying Alive. That actually
really helped. I was teaching my wife how to do CPR for purely selfish And I
told, her that I said, you know, uh, Uh, uh, uh. Staying alive, that's your
beat, right? And so it was actually very helpful and she still remembers it to
this day and what she needs to do. And it was just it helped galvanize her in
doing it and feeling comfortable with it. So that's very helpful. I had a
friend, a physician who cardiac, arrested in his living room and, a perfectly
healthy guy.

It was a mix of a variety of things that happened. He was
probably over caffeinated and some other things had just gotten off a long
flight and just had an arrhythmic event. And his wife who's not medically
trained at all gave him CPR for 10 minutes and was able to keep him alive and
now he's back practicing. So that story sort of, led me to teach my wife how to
do cpr, and really I told her press. Hard as you can and do staying alive. But
I wanted to just ask about the time that you're giving CPR and how much that
matters. So you mentioned there's a time interval before somebody gets CPR and
how critical that is. It's lack of, reduction by 10% per minute of survival
rates. But how about the length of time that people get CPR? How much is that,
associated with prognosis?

Dr. Ben Abella: Yes. and it is to a certain degree, less
so than time without CPR, because after all, it's harder. CPR quality varies so
much. It, sort of depends. That said, we think. Certainly we know of cases
where excellent CPR is provided where people can have a 20 or 30 minute
resuscitation and still make a full recovery. The most amazing example of this,
there was a soccer player, or if we have any listeners from the United Kingdom
a football player on the soccer, on the football pitch in England in Bolton
United Kingdom. This is all on YouTube and around social media. His name was
Fabrice Muamba.

He had a cardiac arrest in the middle of a football and, had an
arrhythmic event, ends up with an ICD. Eventually, he had 78 minutes of cpr. He
had refractory v-fib and they just could not shock him out of it. 78 minutes
and he made a full recovery. Now, that's very unusual, but it does provide
proof of concept that if CPR started promptly and aggressively, that it is
certainly possible to have a viable patient. And so one of the big questions is
how long do you go before you call it? And that is one of the hardest and most
fraught questions I think in resuscitation science, we really don't know.

What we do know is that many cardiac arrests are probably
called too early. And because just because someone's had CPR for 15 or 20
minutes does not mean the case is impossible. Especially now we have so many
more advanced therapies to offer, for example, In many centers we're doing
rescue ECMO, which we call an A pulseless patient, eCPR for endovascular CPR.
We're basically people are put on ECMO circuits while dead, while getting CPR.
And that allows them to be sustained for long periods of time while the
problems are sorted out. So, so the point being that you really want to give it
a solid effort, 20, 30 minutes and that's what's sort of taught in emergency
departments around the country.

Dr. Kendall Williams: So let's talk about the role of
the AED. You mentioned shockable rhythms and so forth. That's a new thing for
many of us. At least the deployment of AEDs in the public spaces, which is
obviously some of the results of your work I know. But let's talk about AEDs.
First of all, what is the benefit to them?

Dr. Ben Abella: Yeah, AEDs are really a remarkable
thing. So automated external defibrillators or AEDs are sort of have become
ubiquitous, you see them in train stations, airports, gyms, but this explosion
of AEDs has really only occurred just in the last 10 to 15 to 20 years. I mean,
it's, really quite recent. They're amazing. What they are is they're
defibrillators, but their secret sauce is it's all automated rhythm analysis so
that you don't have to know ACLS, you don't have to know anything about
rhythms. But, the computer circuitry is such, and the quality has gotten high
enough that they can very rapidly analyze the heart rhythm and determine if a shock
is required, and then they will deliver a shock therapy.

Through pads on the chest. And this is absolutely essential for
people in shockable rhythms of arrests. So ventricular fibrillation of
ventricular tachycardia, which are probably in most centers that have looked at
this, about 30% of all arrests. It very much depends. In young, healthy people,
it's much higher. So DeMar Hamlin certainly had a ventricular fibrillation
arrest. If someone has a non shockable rhythm and the AED won't do anything, that
doesn't mean it shouldn't be hooked up. Indeed, you, we still wanna do that to
make sure you can treat a shockable rhythm, but it will simply say, shock not
advised, and then the AED does nothing.

But for people with shockable rhythm arrests, the early
application of an AED is absolutely lifesaving. And indeed, in DeMar Hamlin's
case, an AED was used and that was the definitive therapy. So he got CPR until
he got a shock. The shock restored his pulse and the rest is history.

Dr. Kendall Williams: I think he had a pulse before he
left the field, which, you know,.

Dr. Ben Abella: Yeah. It's, amazing. And that's not
uncommon when AEDs are employed. So, for example, I work in the HOP emergency
department hospital, university of Pennsylvania, here in, in center City,
Philadelphia, well, west Philly but in the city we every so often get patients
transported from the airport. And the airport is a, place where there's a lot
of witness. And there's a lot of AEDs and so it is not uncommon for us to get
cardiac arrest survivors from the airport who are shocked by the AED at the
airport and come in very much alive.

Dr. Kendall Williams: You know, I looked online to see
how much they cost because I thought , you. Doctor, I should probably have an
AED in my car in case I need to grab it. looks like they're about a thousand
dollars for a reasonable model. Is that what?

Dr. Ben Abella: Yeah. Prices have climbed a little bit
with the covid and interest rates and supply chain issues and all these modern
problems we suffer so, so often they're 1200 to 1400. But yes, there's sort of
within, the zone for, things that one might have as lifesaving equipment. And
yes, I think they can be very, valuable. one of the things that's very exciting
is that recently some newer generation AEDs have been developed that I'm fairly
bullish on full disclosure, I have no relationship with these companies, no
stocks. I'm not selling anything here. But one of the issues that has come up
with AEDs of late over the last decade is they haven't taken full use of
technologies like GPS or wifi or cell service to connect and be useful in that
way.

And here's what I mean. A fire extinguisher is a device with no
connectivity. If your house has a fire, do you know where your fire
extinguisher is? Well, you may or you may not. On the other hand, You also
don't know when's the last time you checked it? Is it charged? Is it dead? But
now, imagine a connected device that goes to your phone that can warn you if
the battery's gonna go low. It can tell you where it is. It can call 911
through the AED and receive messages from 911 through the AED. and there's been
a newer, now FDA approved defibrillator that does just that.

And we're excited about this generation of technologies because
imagine a world in which an AED is in the lobby of a building and someone has a
cardiac arrest, a block away, you wouldn't know. But with a connected AED, it
can actually wake up alarm and show a map of how to get to the victim. So it
basically can create this radius of care because there have been many, many
instances where people didn't even know a defibrillator was in the vicinity,
and they were never applied. So, I think we're gonna see more and more AEDs
with connectivity abilities, which will really enhance saving lives.

Dr. Kendall Williams: Yeah, it's gonna tie into Apple
watches and other devices I'm sure. So that you can.

Dr. Ben Abella: Exactly.

Dr. Kendall Williams: Yeah. DeMar Hamlin, as all cases
would have been put in the ambulance he was intubated in the field. That's part
of standard protocol. I got a lot of questions on Twitter about that, which I
said, it doesn't really mean anything that he was intubated that standard
protocol and then he gets to the hospital and, starts a cardiac arrest
protocol. Can you tell us in broad outlines what that is?

Dr. Ben Abella: Right. So when people get their pulse
back from cardiac arrest a lot of work remains to be done, and this falls under
this rubric of post cardiac rest care. After you don't have a pulse for a
period of. And then your pulses are restored. This triggers a sequence of
events known as ischemia, reperfusion injury, and it can be quite devastating.
You can have brain swelling, inflammatory cascades. It can look like sepsis.
You have endothelial dysfunction. You can develop ATN, all sorts of problems in
the critical care unit can. en Sue, and there are some ways to address this.
And so one of the major therapies that we employ in postcardiac risk care that
Mr. Hamlin certainly got is known as targeted temperature management or TTM.

And the idea here is the precise control of body temperature.
Now, why does that matter? Well, Many patients after cardiac risk develop
fevers from brain dysfunction. They're neurogenic fevers and they've been shown
to be very bad for recovery and worsen brain injuries. So they're not, they're
pathologic fevers, they're not useful in any way. And by controlling and,
mitigating these fevers. And in some instances, and this is a topic of some debate,
but at least it's fair to say in some instances, lowering of core body
temperature. Traditionally we thought of this as lowering to 33 Celsius,
although there is some debate about the appropriate goal temperature.

But by lowering temperature we can actually reduce his
inflammation and brain swelling and improve outcomes. Another key aspect of
post-arrest care. is very aggressive blood pressure management. So many of
these patients become hypotensive and it's been shown that this hypotension is
very bad for the brain because it needs to remain perfused. And in many cases
there's increased icp, increased brain swelling. And so, aggressive maintaining
of mean air arterial pressure targets is another key piece of this. And a third
thing is oxygenation. So too much oxygen is actually a bad thing and. Rapid
weening of FI02 or oxygen inhaled oxygen through the ventilation circuit is
also known to be very protective.

And there's four or five other things that I could go on about
as far as critical care maneuvers. But suffice it to say that many hospitals
have this posters care bundle where they have a set of. Eight to 10 things they
do in the first 24 to 48 hours. And they've been shown to greatly improve
survival through implementing a post-arrest care bundle up pen. We published on
this in 2009, we were able to double survival for patients with their pulse
back who showed up at our emergency department.

Dr. Kendall Williams: So once they get the pulse back,
as you note, you're not out of the woods because there's inflammatory damage
that's being done. Multiple organs that you're trying to support and get people
through. Once the heart and lungs are working and you're, managing renal
failure or whatever. I would imagine most of it comes down to what's the situation
with the brain, right? How much Anoxia was experienced? How do you assess that?

Dr. Ben Abella: Yeah. First off, that's exactly right.
even though the word is cardiac arrest it's really a brain disease and a brain
recovery disease. In fact, some hospitals have protocols where all the
post-arrest patients go to the neuro ICU for that very reason. So it's really a
brain problem. And how do we manage that and monitor that? Well, most patients
fall on cardiac arrest at major centers are put on continuous EEG monitoring.
And this is for a number of reasons. One, it's to look for prognostication
signs how active is the brain, but also many patients post-arrest have
seizures, and we aggressively manage those seizures and sometimes can improve
outcomes.

So continuous EEG is important. Another thing we'll often do in
many hospitals, get an mri, these five to seven, to look for structural
injuries that important information for prognostic purposes. . And then as far
as treating the brain, so certainly managing with anti-seizure medicines when
appropriate, but maintaining, appropriate perfusion through arterial pressure
goals and, lessening of ICP are important. But yeah, ultimately it is a brain
disease. Now, if someone got aggressive, early CPR, they often have very little
brain injury. And I suspect, I mean obviously I haven't treated or seen DeMar
Hamlin.

I would not be surprised if he has no brain injury at all.
Sometimes one doesn't know for weeks to months and there can still be subtle
deficits. But certainly I can say with certainty, we've had a number of
patients come through our hospital who've returned to their families, returned
to work, and for all practical purposes feel back to normal. And their spouses
have reported to us, their memory seems normal, their speech is normal. They go
back to playing tennis, so their fine motor is pretty good. So, it is possible
to return to life as before, which raises a whole other host of issues known as
survivorship issues and co survivorship, which is even then the problems are
not fully solved.

Many people after cardiac arrest have issues with the trauma
they experience, and they sometimes have ptsd. Sometimes they're afraid to
return to activities cuz what might happen sometimes their spouses are afraid
for them to return to exercise or other activities for fear of what might
happen. So there's a complex host of psychosocial issues and sometimes
occupational therapy and physical therapy issues that need to be addressed
after cardiac arrest and there's science behind some of these things. And so
one of the things I think it's important to put to the primary care community
is, There is help out there and I would imagine if someone goes to see a new
internist or maybe a return visit and they say, oh, I had a cardiac arrest six
months ago.

I seem to be fine. And the primary care doctor says, well,
gosh, I'm glad you're okay. But this is not something I do very much. I don't
know what sort of follow-up you need. It's important to know that these
patients do have issues that need follow up and following up with a
cardiologist isn't sufficient. Many of these patients need a psychiatry. Many
of these patients need PT and OT evals. Because there are subtle effects for
cardiac arrest that, that we can manage and actually improve the quality of
life.

Dr. Kendall Williams: Does everyone, regardless of cause
need an a ICD?

Dr. Ben Abella: That's a great question. No. Some people
need an ICD, but many do not. it's a complicated area to do justice to it. But,
I can say this briefly. The most common indication for an ICD after cardiac. Is
that someone had a shockable rhythm, so they had ventricular fibrillation of
ventricular tachycardia, and on subsequent coronary angiography, they have no
coronary disease. So a shockable, unexplained shockable arrest with no coronary
disease in most cases gets an ICD.

Now in a sense, DeMar Hamlin, was that the difference there is
he probably will never know for sure, but he probably had Kamodio Cordes. So
there will be quite some discussion and debate, I suspect, among his
cardiologists about whether he gets an ICD or not. But if he wasn't an elite
athlete who would be afraid of returning to the field with such a thing in his
chest, most people like him who have a shockable rhythm arrest with no coronary
disease, as I'm sure he does not, would get an ICD.

Dr. Kendall Williams: Yeah. You mentioned Kamodio Cordes,
and I remember this coming up when I was an early faculty member and there's a
New England Journal article on it. Where Patients, usually young people, he was
a little old for it. I believe get a blow to the chest. That just, the,
pressure blow leads to an arrhythmia. And so it's completely reversible if he
gets immediate care and everything else. But your life is in danger in those
few moments. So he basically had V-fib due to that tackle. Right.

 That's presumed.

Dr. Ben Abella: That's right. that's what we, think
happened. it's sort of a diagnosis of exclusion. There's no sort of telltale
findings afterwards, so it's hard to know. But yes. Anyone interested in this?
one of the lead guys in developing science and Kamodio Cordes is the
electrophysiologist at UT southwestern named Mark Lank L A N K, and he was one
of the authors of some new England Journal paper that described this. But yeah,
a sudden sharp blow to the chest timed exactly with a short segment. We believe
it's about 20 milliseconds duration in the repolarization cycle can sometimes
trigger vtac and or vfib and or Vtac that degenerates the vfib. So you have to
be really unlucky. It has to be a blow in exactly the right place.

Generally at the apex of the heart. It has to be enough energy.
And in his study, where they had pig model of this, it had to be a baseball of
at least 40. miles per hour of velocity. So you actually did velocity testing.
So it's gotta be a hard hit with a lot of energy and it generally does not
afflict people in their twenties. It's often a teenager thing. And the thinking
there, and I've spoken to Dr. Lank about this, no one knows for sure, but the
theory there is that young chess are more flexible and compliant. And so the
energy is transmitted. As you get into adulthood, twenties, thirties, ribs and
sternum break and they absorb a tremendous amount of the energy.

And so less is transmitted to the heart than a more flexible
system where it would. So, yeah, DeMar Hamlin, I think is 24, and that is old.
The peak incidence for Kamodio cordes is definitely in the teens. if anyone is
curious, the, the most common sports to have Kamodio Cordes courses cases are
baseball and softball. And so those projectiles, a line drive hit that nails
the shortstop or the pitcher in the chest, that's a high velocity, high impact
thing. And every year there's a few little leaguers who have Kamodio cordes. it
can also happen, by the way, in the lacrosse field, lacrosse balls are very
hard and thrown fast. The difference there is, and most lacrosse players, if
I'm not mistaken, have chest guards of some form, whereas baseball players,
unless you're a catcher, do not.

So a pitcher and a shortstop and a second basement do not wear
a chest protection, whether they should. That's a whole other conversation for
another day. But thankfully there's not a lot of cases, but it does happen.

Dr. Kendall Williams: And it's important for anybody
involved in youth sports to be aware of it and aware of at least what needs to
be done immediately when you see somebody go down,.

Dr. Ben Abella: That's right. And in fact, an important
principle that is being, pushed to youth sports is at, little League baseball
games, little league stadiums should have AEDs and many still do not. But this
is something that is being actively promoted and advocated for that facilities
that handle sports. Like baseball or softball should have AEDs. Oh, by the way,
another sport where this happens is hockey. There was a well-known case of an
NHL player who had kamo accords from a strong puck strike to the chest. He made
a full recovery. So hockey as well is, a sport where having AEDs available is
so important.

Dr. Kendall Williams: Well, Ben, this has been great. I
wanted to have you on. It's timely, it's an opportunity for us all to educate
ourselves so that we can educate our patients. It's an opportunity for us all
to just remember what we're supposed to do, if we see something like this in
front of us. And I would say that most people, I was thinking about this the
other day, most people will see chest compressions being delivered in a public
setting in their lifetime. I think I've seen it three or four times, where a
baseball game or different places. So, we're gonna see these things happen and,
to be able to at least get the process started, give good chest compressions
very quickly and be able to get the proper professionals there is the key
thing.

Dr. Ben Abella: Yes, I think that's right.

Dr. Kendall Williams: So Ben, we'll have you back when
we want to delve into this topic. Again, I really appreciate your time and I
appreciate the audience time to come and listen to the Penn Primary Care
podcast. Please join us again next time.

Disclosure: Please note that this podcast is for
educational purposes only. For specific questions, please contact your
physician. And if an emergency, please call 911 or go to the nearest emergency
department.