In light of a recent confirmed case of Naegleria fowleri—commonly known as the “brain-eating amoeba”—in South Carolina, we spoke with Dr. Anna Kathryn Burch, MD, a pediatric infectious disease physician at Prisma Health Children’s Hospital. With her expertise and firsthand experience treating these rare but devastating infections, Dr. Burch offers insights into how the amoeba spreads, what symptoms to watch for, and how families can protect themselves during summer water activities.