EP 1043B - The Science Behind Why Some of Us Might Be Inclined to Eat More Than Others

New results from PREDICT, the largest ongoing nutritional research program in the world that looks at responses to food in real-life settings, show that people who experience big dips in blood sugar levels, several hours after eating, end up feeling hungrier and consuming hundreds of more calories during the day than others.

Published last month in Nature Metabolism, the research team at health science company ZOE found why some people struggle to lose weight, even on calorie-controlled diets, and highlight the importance of understanding personal metabolism when it comes to diet and health.

The research team collected detailed data about blood sugar responses and other markers of health from 1,070 people after eating standardized breakfasts and freely chosen meals over a two-week period, adding up to more than 8,000 breakfasts and 70,000 meals in total. The standard breakfasts were based on muffins containing the same amount of calories but varying in composition in terms of carbohydrates, protein, fat, and fibre. Participants also carried out a fasting blood sugar response test (oral glucose tolerance test), to measure how well their body processes sugar.

Tim Spector joins us today to tell us more about this study and its use of twins to explore eating habits. He is a Professor of Genetic Epidemiology at King’s College London and a scientific co-founder of ZOE.

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Bonus
How Your Diet Affects Your Risk for Cancer



EP 1043B - The Science Behind Why Some of Us Might Be Inclined to Eat More Than Others
Featuring:
Tim Spector
Tim Spector, Professor of Genetic Epidemiology at King’s College London and scientific co-founder of ZOE, concludes, “Food is complex and humans are complicated, but our research is finally starting to open up the black box between diet and health. I use the UK twins registry (TWINSUK) of 10,000 twins to pursue gene discovery in the common complex traits and diseases via genetic epidemiology. I study a wide variety of diseases from back pain to anxiety, snoring to sexuality. Our group focus on age-related diseases such as CVD, metabolic traits, locomotor problems such as osteoporosis and osteoarthritis, cognitive function, and eye disorders. We have genome-wide scans and expression data on large numbers of twins.

Instagram: @zoe