A Mount Sinai research team has identified one of the mechanisms that establish the skin as a protective barrier, a breakthrough that is critical to understanding and treating common skin conditions including eczema and psoriasis.

One of the most important roles of the skin is to act as a barrier that prevents water loss and protects the skin from pathogens. Failure of this protective function contributes to dermatological diseases. The research team led by Sarah E. Millar, Ph.D., Director of the Black Family Stem Cell Institute at the Icahn School of Medicine at Mount Sinai, found that the scaffolding protein,  histone deacetylase 3 (HDAC3), is essential for proper skin development and barrier formation.

Dr. Millar joins Dr. Roizen to talk about her team's findings and what they mean for those suffering from some skin conditions. 

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